he brand bbi-biotech is a well-known synonym for innovative fermentors and bioreactors.
The bbi-biotech GmbH offers equipment and services for all process applications within
biotechnology, pharmaceutical, cosmetic and food industry.
bbi-biotech has developed its own portfolio for standard bioreactor vessels as well as for disposable
systems disposable systems of 3rd party suppliers. We succeeded in the development of a modular
cultivation system for all different kinds of cells and microorganisms via the joint
combination of newest technologies with decades of application experience.
The xCUBIO is a bioreactor toolbox with predefined modules, which are selected
by your demands and which are combined quickly to your personal solution.
Beside the development and production of instruments bbi is offering lectures
and technical services. Another central issue of bbi-biotech’s activities is the
innovative sampling system bioPROBE for automatic dead-volume-free sampling
of fluids to combine cultivation and downstream systems with process analytics.
Fermenters and Bioreactors
Each xCUBIO Bioreactor or Fermenter integrates the highest diversity of available
sensor, control, analysis and peripheral technologies via its unreached modular construction within
just one single case with central operation terminal:
◾ Free pump selection
◾ Free balance connections
◾ Integrated exhaust analysis
◾ integrated gas mix units
◾ integration of arbitrary external analytics
◾ Integration into SCADA-systems
◾ Cultivation vessels of every type and scale, also refurbished
◾ Integrated automatic sampling system bioPROBE for the atline-integration of
further analytical devices - the real PAT!
Customized Bioprocess Engineering
bbi-biotech executes your project on demand, reliable and
in time. We modernize your old vessels, upgrade them to current
or assemble new vessels
according to your design.
We engineer bioreactors
and the utility technologies
for your biotechnological
production and supply basic
and detail engineering as well
as the whole installation – all
from one source.
Sampling System bioPROBE
bbi-biotech supplies automatic sampling systems for all applications within
biotechnology, pharmaceutical, food, cosmetics and chemical industry.
Sampling systems by bbi-biotech connect all offline-analytical instruments to
every bioreactor type. Bioreactor vessels from stainless steel, glass or
disposable materials like bags can be equipped directly or in a bypass.
Embedded in a sterile air cushion, the samples are piped through a hose to
the analytical instrument. Our plastic or steel probes and all hose materials
are produced in a cleanroom and are pre-sterilised.
xCUBIO single One single vessel with maximal equipment! Customize the selection: simple systems for aerobic bacteria cultivation can easily be modified for high cell density processes. Even highly sophisticated and completely equipped perfusion systems for mammal cell culture are realized with xCUBIO single
xCUBIO twinThe first scale process within just one single installation! Cultivate in absolutely parallel conditions or scale your process by the factor 1:20 – all in one system. Variable vessels and equipment selections access all opportunities.
xCUBIO multiR&D-Cultivation in up to 12 parallel vessels! Start your installation with the first two vessels and continue step by step – simply by Ethernet plug-in installation. Realize a really compact installation with complete and exactly customized equipment selection!
xCUBIO in-situCIP/SIP-technology for high-end applications! Wherever purity and reliable sterility are urgently required or the system scale requires cleaning on site. Fully automated sequences, semi-automatic design or integration into upstream cascades: it is your decision.
xCUBIO retrofitThe economic upgrade of existing bioreactors and fermenters from every type and manufacturer! Protect your investments with a plug-in-compatible refurbishment, if your installations get aged or damaged. Exact system rebuilt and technology integration included!